Kenya Veterinary Vaccines Production Institute
 

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PESTEVAX TM

 Live Attenuated PPR Virus Vaccine
COMPOSITION
PESTEVAXTM is a freeze-dried live attenuated PPR virus vaccine prepared from the Nigerian strain 75/1. It contains not less than 10 2.5 TCID 50 per d1 ml dose .The diluent is used to re-hydrate the freeze-dried component.

PROPERTIES

Peste Des Petits Ruminants (PPR) is an acute, highly contagious, fatal viral disease of small ruminants (Sheep and Goats).The disease is caused by a mobillivirus in the family Paramyxoviridae. Clinically, the disease is characterised by pyrexia (fever), erosive stomatitis, conjunctivitis, gastroenteritis and bronchopneumonia. Alimentary tract involvement is marked by the development of severe diarrhoea. Since there is no specific treatment for PPR, the disease can be controlled by carrying out preventive measures through vaccination of sheep and goats.

INDICATIONS

For the active immunisation of healthy Sheep and Goats against PPR.

DOSAGE AND ADMINISTRATION

Reconstitute each vial with the corresponding sterile diluent. Keep the reconstituted vaccine cool and protected from sunlight. Take reasonable aseptic precautions in reconstituting and withdrawing the vaccine. Administer via the subcutaneous route to animals of at least 4 months of age at the rate of 1ml per animal. Annual booster is recommended.

CONTRA-INDICATIONS, WARNINGS

For Veterinary use only. Do not use if seal is broken or package is damaged. Do not vaccinate un-healthy animals. Do not freeze reconstituted vaccine. Do not expose the vaccine to sunlight. All vaccines may occasionally cause anaphylactic reactions in some animals. If this occurs adrenaline should be administered.

STORAGE

Store at  -200C. (Freezer). Under these conditions, the shelf life is 2 years. If stored at between +20C and +80 C (refrigerator) the shelf life is one month. Once the vaccine has been reconstituted, it must be used immediately ( within 2 hours if chilled or within 1 hour in case not chilled) and any remaining quantity discarded.

PRESENTATION

50, and 100-dose vials packed together with the corresponding diluent.  
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